Quatrefolic is the most popular type of folate among pregnant women today due to its many advantages over other forms of folate. So what are these differences? Let’s find out with Khoi Nguyen through the article below!
1. Folic acid role for pregnant women
The neural tube is a small band of tissue that then coils its length to form a tube, which will later develop into the brain and spinal cord. If this process takes place at the wrong time, the neural tube of the fetus will not close completely and will later create defects for the baby: spina bifida, craniocervical defect, …
Folic acid is a B vitamin that plays an important role in hematopoiesis and DNA replication. Folic acid has been studied to prevent neural tube defects by up to 70%. Therefore, this is a very important substance, which should be supplemented by the pregnant mother at the right time for the normal and healthy development of the fetus.
2. Generations of folic acid
Quatrefolic is a form of folic acid developed by Gnosis by Lesaffre, whose molecular formula is the glucosamine salt of (6S)-5-methyltetrahydrofolate. The formula has been patented by the company since 2008.
Advantages of Quatrefolic
When comparing the pharmacokinetics of Quatrefolic with the calcium salt form of 5-MTHF and the synthetic form of folic acid, Quatrefolic showed the highest absorption concentration and the highest AUC compared with the other two forms. This demonstrates that Quatrefolic is the most bioavailable form of folic acid.
Water solubility plays a very important role in the absorption of active ingredients into the body. The higher the solubility, the better the active substance is absorbed through the mucosal cells to enter the circulation, thus the bioavailability will be improved. Quatrefolic is 100 times more soluble than the calcium salt form of 5-MTHF. This could therefore explain why the bioavailability of Quatrefolic is superior to that of older generations.
Nutristill 90 is a supplementary product imported by Khoi Nguyen Medical Import-Export Co., Ltd directly from Italy. The product contains many vitamins and minerals, especially Quatrefolic with high content, to help provide enough nutrients for pregnant women and fetuses during pregnancy with only 1 tablet per day. You can find more detailed information about the product here